2014年1月9日 星期四

Absinthe: A literary muse


苦艾酒英語Absinthe 收聽i/ˈæbsɪnθ/ AB-sinth/ˈæbsænθ/ AB-santh; 法語Absinthe: [absɛ̃t]),歷史上描述為蒸餾的,高酒精度數(45-74%ABV,酒精純度90-148)的一種飲料[1][2][3][4]。它是一種茴香味的烈酒,從植物性藥材中萃取,其中包括苦艾(Artemisia Absinthium,又名「大艾草」Grand Wormwood)的花和葉,綠茴芹(green anise),甜茴香(sweet fennel),和其他藥材和食用香草。苦艾酒歷來有一種天然的綠色,但也有是無色的。歷史文獻中通常稱之為「法語la fée verte」(綠妖精、綠精靈、綠仙子)。雖然有時它被誤作為利口酒的一種,傳統上苦艾酒瓶裝時是不加糖的,因此,將其歸類為烈酒[5]。傳統瓶裝的苦艾酒酒精度數很高,但飲用前通常使用水進行稀釋。
18世紀後期,苦艾酒興起於瑞士納沙泰爾州(Neuchâtel)。在19世紀末和20世紀初,它成為法國大受歡迎的酒精飲料,尤其是在巴黎的藝術家和作家之間。由於其與波希米亞文化之間的因緣,苦艾酒受到社會保守主義者和禁酒主義者的反對。歐內斯特·海明威(Ernest Hemingway)、夏爾·皮埃爾·波德萊爾(Charles Pierre Baudelaire)、保羅·魏爾倫(Paul Verlaine)、阿蒂爾·蘭波(Arthur Rimbaud)、亨利·德·土魯斯-洛特雷克(Henri de Toulouse-Lautrec)、阿梅代奧·莫迪利亞尼(Amedeo Modigliani)、文森特·梵谷(Vincent van Gogh)、奧斯卡·王爾德(Oscar Wilde)、阿萊斯特·克勞利(Aleister Crowley)以及阿爾弗雷德·雅里(Alfred Jarry)都是知名的苦艾酒的擁躉。[6]
苦艾酒也經常被描繪成一個危險的容易上癮的精神藥物[7]。苦艾酒中含有的微量化合物側柏酮(thujone),被指含有毒副作用。到1915年在美國歐洲大部分國家,包括法國荷蘭比利時瑞士奧匈帝國,苦艾酒都被取締。雖然苦艾酒受到詆毀,人們卻一直無法證明苦艾酒比普通白酒危險程度更大。撇開酒精本身的作用不說,苦艾酒對人造成的精神影響被誇大了[7]。20世紀90年代,近代的歐盟食品和飲料相關法律取消了針對苦艾酒生產和銷售長期存在的限制,苦艾酒開始復興。由21世紀初,在十幾個國家中崛起了近200個苦艾酒品牌,其中最引人注目的是瑞士美國西班牙法國捷克共和國的品牌。

詞源

苦艾酒英文為Absinthe,其實是一個法語單詞,在法語中一般指酒精飲料,偶爾也可以指艾草植物,包括稱為大苦艾(grande absinthe)的中亞苦蒿(Artemisia absinthium),和小苦艾(petite absinthe)的西北蒿(Artemisia pontica)。其拉丁名artemisia來自古希臘的狩獵女神阿爾忒彌斯(Artemis)。單詞Absinthe來自拉丁語Absinthium,而Absinthium又是希臘語ἀψίνθιον(apsínthion)拉丁化而成的,它們的本義都是「艾草」(wormwood)[8]。將苦艾用於飲料可以從盧克萊修(Lucretius)的著作《物性論》(De Rerum Natura(I 936-950 ))中得到引證,盧克萊修表示,含有艾草(wormwood)的飲料可以作為作為兒童的藥飲,伴著蜂蜜喝使其容易飲用。使用了詩歌的形式,將這個複雜的理念用比喻的方式講述了出來[9]
有些人聲稱,ἀψίνθιον這個詞在希臘語中的意思是「不能飲用」,但它可解析為波斯詞根spandaspand,或其變體esfand,意思是駱駝蓬(Peganum Harmala),也被稱為敘利亞芸香(Syrian Rue),但它實際上不是芸香(另一種著名的苦味的草藥)的品種。是否這個詞是從波斯語引入到希臘,或兩者從共同的語源進化而來,目前還不清楚[10]
absinthe的變體包括absinthabsynthe,和absenta。在歐洲中部和東部生產苦艾酒的地區,Absinth(不包括結尾的e)是最常見的拼寫變異,並特指波西米亞風格的苦艾酒[11]

不像蘇格蘭威士忌白蘭地金酒在 全球範圍內都規範並定義了製作方法和原料,大多數國家都沒有苦艾酒的法律定義。因此,生產者可以任意的在他們的產品上標上「苦艾酒」 ("absinthe" 或"absinth")的標籤,而不受任何法規限制,也沒有標準評判其質量。 合法的苦艾酒生產者遵循歷史上流傳的兩個製造流程中的一個:蒸餾法(distillation)或低溫混合法(cold mixing)。在那些有法規定義苦艾酒的國家(比如瑞士),只允許通過蒸餾生產苦艾酒[57]


Absinthe: A literary muse

Jane Ciabattari investigates how the powerful spirit that drove Vincent Van Gogh to cut off his ear also inspired great authors from Arthur Rimbaud to Ernest Hemingway.


Absinthe: How the Green Fairy became literature’s drink


HIDE CAPTION
The green stuff
Absinthe, a green liquor with ten times the alcohol content of wine and popular with legendary authors and artists, was banned for most of the past century. (Goran Heckler/Alamy)
Absinthe has inspired many great authors of the last 150 years – and may have ruined some as well. Jane Ciabattari investigates the green spirit’s peculiar power.

Arthur Rimbaud called absinthe the “sagebrush of the glaciers”  because a key ingredient, the bitter-tasting herb Artemisia absinthium or wormwood, is plentiful in the icy Val-de-Travers region of Switzerland. That is where the legendary aromatic drink that came to symbolise decadence was invented in the late 18th Century. It’s hard to overstate absinthe’s cultural impact – or imagine a contemporary equivalent.
The spirit was a muse extraordinaire from 1859, when Édouard Manet’s The Absinthe Drinker shocked the annual Salon de Paris, to 1914, when Pablo Picasso created his painted bronze sculpture, The Glass of Absinthe. During the Belle Époque, the Green Fairy – nicknamed after its distinctive colour – was the drink of choice for so many writers and artists in Paris that five o’clock was known as the Green Hour, a happy hour when cafes filled with drinkers sitting with glasses of the verdant liquor. Absinthe solidified or destroyed friendships, and created visions and dream-like states that filtered into artistic work. It shaped Symbolism, Surrealism, Modernism, Impressionism, Post-Impressionism and Cubism. Dozens of artists took as their subjects absinthe drinkers and the ritual paraphernalia: a glass, slotted spoon, sugar cubes – sugar softened the bitter bite of cheaper brands – and fountains dripping cold water to dilute the liquor.
Absinthe was, at its conception, not unlike other medicinal herbal preparations (vermouth, the German word for wormwood, among them). Its licorice flavor derived from fennel and anise. But this was an aperitif capable of creating blackouts, pass-outs, hallucinations and bizarre behavior, with nearly ten times the alcohol content of wine. Contemporary analysis indicates that the chemical thujone in wormwood was present in such minute quantities in properly distilled absinthe as to cause little psychoactive effect. It’s more likely that the damage was done by severe alcohol poisoning from drinking twelve to twenty shots a day. Still, the mystique remains.
Muse in a bottle
Rimbaud, Baudelaire, Paul Verlaine, Emile Zola, Alfred Jarry and Oscar Wilde were among scores of writers who were notorious absinthe drinkers. Jarry insisted on drinking his absinthe straight; Baudelaire also used laudanum and opium; Rimbaud combined it with hashish. They wrote of its addictive appeal and effect on the creative process, and set their work in an absinthe-saturated milieu.
In the poem Poison, from his 1857 volume The Flowers of Evil, Baudelaire ranked absinthe ahead of wine and opium: “None of which equals the poison welling up in your eyes that show me my poor soul reversed, my dreams throng to drink at those green distorting pools."
Rimbaud, who “saw poetry as alchemical, a way of changing reality” Edmund White notes in his biography of the poet, saw absinthe as an artistic tool. Rimbaud’s manifesto was unambiguous: he declared that a poet “makes himself a seer through a long, prodigious and rational disordering of all the senses.” Absinthe, with its hallucinogenic effects, could achieve just that.
Guy de Maupassant imbibed, as did characters in many of his short stories. His A Queer Night in Paris features a provincial notary who wangles an invitation to a party in the studio of an acclaimed painter. He drinks so much absinthe he tries to waltz with his chair and then falls to the ground. From that moment he forgets everything, and wakes up naked in a strange bed.
Contemporaries cited absinthe as shortening the lives of Baudelaire, Jarry and poets Verlaine and Alfred de Musset, among others. It may even have precipitated Vincent Van Gogh cutting off his ear. Blamed for causing psychosis, even murder, by 1915 absinthe was banned in France, Switzerland, the US and most of Europe.
Cultural hangover
The Green Fairy faded as a cultural influence for most of the 20th Century, to be replaced by cocktails, martinis and, in the 1960s, a panoply of mind-altering drugs. There were occasional echoes of its power, though mostly nostalgic.
Ernest Hemingway sipped the Green Fairy in Spain in the 1920s as a journalist, and later during the Spanish Civil War. His character Jake Barnes consoles himself with absinthe after Lady Brett runs off with the bullfighter in The Sun Also Rises. In For Whom the Bell Tolls, Robert Jordan brings along a canteen of the stuff. In Death in the Afternoon Hemingway explains he stopped bullfighting because he couldn’t do it happily “except after drinking three or four absinthes, which, while they inflamed my courage, slightly distorted my reflexes."
Hemingway even invented a Death in the Afternoon cocktail for a 1935 celebrity drinks book: “Pour one jigger absinthe into a Champagne glass. Add iced Champagne until it attains the proper opalescent milkiness. Drink three to five of these slowly."
In the late 20th Century, absinthe became a decadent reference point among a new generation of writers based in latter-day Bohemian outposts like San Francisco and New Orleans.
"The absinthe cauterized my throat with its flavor, part pepper, part licorice, part rot,” wrote precocious New Orleans horror writer Poppy Z Brite in a 1989 story, His Mouth Will Taste of Wormwood. The narrator and his boyfriend, jaded grave robbers, have found more than fifty bottles of the now-outlawed liquor, sealed up in a New Orleans family tomb. By the end, the narrator is fantasising about his first bitter kiss of the spirit from beyond the grave.
Still seeing green
Today’s absinthe is a “tongue-numbing drink” that “sharpens the senses,” says Lance Winters, master distiller and proprietor at St George Spirits, which offered the first legal absinthe in the US in late 2007.
“To my mind, absinthe imparts an air of the mystic, a touch of the supernatural – qualities I like in a drink now and again,” says Rosie Schaap, drinks columnist for The New York Times. She recommends “deploying the stuff with a light hand.” Her contemporary absinthe cocktails include the Fascinator – two parts gin, one part dry vermouth, two dashes of absinthe and one mint leaf.
In today’s literary circles, absinthe is more an amusement than a muse – showing up as a hipster cocktail at themed book-launch parties. Now widely available, in versions from the recently-made to the $10,000 a bottle vintage Pernod Fils, the drink seems just another popular culture reference, showing up in a Mad Men episode, as a Marilyn Manson-endorsed signature brand, Mansinthe, and inspiring innumerable drinks recipes, many of which use absinthe as a rinse, not a serious ingredient.  You can even buy absinthe dilution apps for your smartphone.
Like the splash added to a cocktail, a literary reference to absinthe today adds a whiff of atmosphere, a reminder of the provocative and form-fracturing writers of the Belle Époque – and that a spirit can indeed inspire.

2013年12月3日 星期二

人到老年

許多事等您老了才明白...



◎人到老年,會突然醒悟:生命是有盡頭的。

這種感悟會使他們行動起來,
去做一些他們很想做但以前總也沒有做的事情,有時,他們甚至用他們意料不到的方式。



◎人到老年,才真正認識自己:也才真正屬於自己,並且用一種寬容、舒適和誠實的方式接受自己。



◎人到老年,方才明白:

東奔西走竭力想去改變的不是別的,恰恰是他們自己。

幾十年的時光換來的不是別的,而是心靜如水。



◎人到老年,開始明白,老年自有老年的風景。

青春雖然美麗,但它會隨時間的流逝而褪色,而青春的心境才是生命中一道不變的風景



◎人到老 年,能冷靜地去看待婚姻和家庭。

他們知道世上沒有完全合乎男人心意的女人,也沒有完全合乎女人心意的男人。



◎人到老年,已懂得安慰自己:並且學會了在似乎無盡的黑暗中為自己點一盞希望的燈。



◎人到老年,看人看事不像過去那麼簡單。因此,不必非得按別人的主意行事。



◎人到老年,開始明白,世事並非黑白分明,在黑白之間往往有一系列的中間色。



◎人到老年,開始明白:人生一世,無論成功與失敗,歡樂與痛苦,盛衰與榮辱,都如自然流水,從那裡來還將到那裡去。於是,寧靜致遠。



◎人到老年,開始明白,衰老不是從中年開始,而是從對生活的厭倦開始的。



◎人到老年,開始明白:孤獨、寂寞、痛苦、失敗,是人生不可缺少的 調味品,因此,善待它們,就是善待真實的人生。



◎人到老年,不再有少年的狂妄、青年的浪漫,人到老年,不再擁有童年的笑臉和青春的美麗,卻常在午夜夢迴。多的則是對生活的感悟和理解。



◎人到老年,能坦然地面對自己的平凡。

他們明白,並非人人都能成功,人人都能大有作為;一生的事業,只要自己奮鬥過、追求過,失敗了又何妨?



◎人到老年,胸懷要開始變得像大海一樣,裝得下四海風雲,容得下千古恩怨。

2013年10月19日 星期六

Good Beer in Berlin? Finally, Yes

Pursuits

Good Beer in Berlin? Finally, Yes

Gordon Welters for The New York Times
The brewpub Hops & Barley, one of the city’s first craft beer destinations.

Gendarmenmarkt, lined with imposing buildings like the French Cathedral and the Konzerthaus, may be Berlin’s most beautiful square. But just a block away, the setting looked like the rest of the central German capital: a mix of cranes, construction sites and creative parking.

Gordon Welters for The New York Times
Raising glasses at Eschenbräu, a beer destination in Wedding.
Gordon Welters for The New York Times
Assessing the quality of the product at Eschenbräu.
Stepping in from a smaller square, the Hausvogteiplatz, I entered a pub that appeared to honor the greatest of German traditions, at least at first glance. In contrast to the modern architecture outside, the room had well-worn, old-fashioned furniture like Alpine chairs with hearts carved into the backs. A collection of cuckoo clocks quietly beat time on the walls. From large platters arose the hearty scents of bockwurst, while the in-house bakery sent out the doughy scent of freshly baked schrippen, Berlin’s crunchy-crusted bread roll.
Once I took a seat, however, the pub, called Meisterstück,  began to reveal unexpected angles. I had certainly never tasted better sausages than Meisterstück’s juicy Coburger bratwurst, though I also couldn’t remember any other links that had been accompanied by a side of wasabi-spiced sauerkraut. Even more surprising were the portraits on the wall, featuring not locals, but some of the best-known faces of international craft brewing. In the back: wasn’t that a picture of Matt Brynildson, brew master at Firestone Walker in California?
And why, in a city long known as a good-beer desert, did the pub’s beer list include not only bottles of Mr. Brynildson’s excellent Pale 31, but also an array of stars like Boon Gueuze from Belgium and the Xyauyù barley wine from Italy’s cult favorite Le Baladin, as well as rare German microbrews?
“You can feel that there’s something coming,” said Johannes Heidenpeter, who opened one of Berlin’s newest craft breweries, Heidenpeters, in the gritty-but-hip central neighborhood of Kreuzberg last December. “I think the time is good to change the taste of beer.”
Mr. Heidenpeter may represent the most iconoclastic and cosmopolitan take on Berlin’s newly developing beer culture: instead of traditional German lager yeast, he praises the aromas from the Belgian and English ale yeasts, and he eschews his own country’s favorite pale lager style of pilsner, or pils. Instead, as he explained when we met up the next day, his brewery offers an American-style pale ale as its standard pint, which uses non-German hops such as Cascade and Amarillo.
“I don’t have a pils and I don’t want to brew a pils,” he said.
Sipping his brewery’s excellent amber ale, Thirsty Lady, I didn’t think anyone who loved good brews would complain, a marked contrast to the longstanding charges that Berlin’s beer culture is lackluster. This is, after all, a place where it has long been more difficult to find a decent version of the city’s own beer style, Berliner Weisse, than in at least a half-dozen American towns, and where the ubiquitous Berliner Pilsner has a dismal ranking in the bottom third of all beers in its category on RateBeer. While it might be Europe’s hipster Hauptstadt, the home of famous writers, musicians and other creative characters, those of us who lived elsewhere could at least console ourselves with the fact that Berlin’s beer was terrible.
But not anymore. In the last few years, a slew of new microbreweries, beer bars and bottle shops has opened in Berlin, and the city’s first craft beer festival, Braufest, took place in September. After hearing about the new developments, I spent a few days visiting friends and trying to figure out how much Berlin’s beer scene had changed, starting out at the 18-month-old Meisterstück, said to be the city’s first craft beer bar. After sampling the brews, sausages and sauerkraut, I went from there to the central Moabit neighborhood, north of Tiergarten park.
I first stopped to check in on the city’s favorite source for great bottles, the Berlin Bier Shop, whose owner, Rainer Wallisser, had helped kick-start the local interest in beer when he began selling Belgian imports like Cantillon and 3 Fonteinen in his wine shop about four years earlier. After looking over the new arrivals and sharing tips with a pack of young beer lovers visiting from Norway, I wandered a few blocks north and west through the Kleiner Tiergarten park until I found Arminiusstrasse and its Markthalle, a sprawling market hall filled with Vietnamese noodle stands, butcher shops and plenty of stuff in between, including BrewBaker, one of the city’s first brewers to make interesting beers. When I arrived, the owner, Michael Schwab, was just finishing up the day’s brew, a relatively unusual amber style known as Vienna lager. He had been making beer since 2006, he told me, but he had only moved to this location in 2011, and had brewed some 120 different recipes since then, including traditional German styles and new arrivals (in local terms) like stouts and ales. In Berlin, he said: “people are more and more interested in different types of beers, not just German beers. Now in Berlin, nearly every brewery has something like an IPA.”
As with much of creative brewing, that “something” seemed open to interpretation. Meeting my friends at the five-year-old Hops & Barley, a brewpub in a former butcher shop in Friedrichshain, we discovered that the house oddball was actually a traditional pils-style pale lager, but one which had been transformed by the addition of Centennial hops, a broad-shouldered American hop cultivar that added a crisp, citrusy aroma. It was a clear favorite for the crowd of friendly locals who had packed into the tiny front barroom.
Not far away, we joined old-school punk rockers and punks a generation or two younger watching the German national soccer team beat up on Kazakhstan in the dark, smoky dive bar known as Bierkombinat Kreuzberg, or BKK. Here, the flavor bomb was an IPA by the neighborhood’s Schoppe Bräu brewery: a pale ale with light caramel and toffee flavors from the malt with grapefruit and a touch of bubble gum from New World hops.
The next day, I bumped into that beer’s creator, Thorsten Schoppe, at the Südstern brewpub in Kreuzberg, where he makes his own Schoppe beers and those for Südstern, including an excellent rye ale. This summer he opened a new brewpub, called Pfefferbräu, in the old Pfefferberg building in Prenzlauer Berg.
But not everything is taking place in such cool neighborhoods. As I discovered later that day, the unlikely northwestern inner-city district of Wedding now serves some of the city’s best beer, thanks largely to a brewpub called Eschenbräu. Set in the basement of what seems to be a student dormitory, the place had its own hop-inflected special brew, a very bitter Schwarzbier called Black Mamba. Eschenbräu’s pils, as well, seemed more fragrant and bitter than most versions I could remember encountering anywhere in Germany.
After Eschenbräu, I stepped down the same street to a year-and-a-half-old specialty beer shop, Hopfen & Malz, where I explained my interest in local beer to the owner, Ludger Berges. After ringing up his last customers, he disappeared into the back, returning with a rarity: a bottle of Bogk-Bier Berliner Weisse, a new, small-batch version of the city’s traditional beer style. Financed by a crowd-funding campaign, it had been oversubscribed by more than 700 percent, perhaps reflecting the dissatisfaction many fans of Berliner Weisse felt toward the lone industrial version still produced in Berlin. It had not yet been released (at that point, it didn’t yet have a single rating on RateBeer),  but Mr. Berges said he hoped to have it in stock soon, and asked if I wanted to join him in trying it. Tasting it in the shop, I was floored by the brew’s character: a cloudy pale yellow with almost no head, it had the lemony sourness of a good Berliner Weisse, but was tempered with light fruity malt flavors and a wild, almost animal-like aroma from the use of the local Brettanomyces yeast, a type of wild fungus that had been chased out of industrial Berliner Weisse production many years ago. I was already planning my next trip back to Berlin to pick up a few cases when Mr. Berges asked if I had heard about the young Americans who were opening a brewpub just around the corner. Armed with instructions, I crossed the street, passing through a hochschule campus and wandering through the small square called Zeppelinplatz. On the other side, I entered a neighborhood called the Brüsseler Kiez, whose streets were mostly named after Belgian cities. A few minutes later I came upon yet another Berlin construction site.
At that point the place had not yet opened, and I found two of the three owners, Matt Walthall and Tom Crozier, installing equipment in the high-ceilinged ground floor of an old Berlin apartment building. They had been friends growing up in Maryland, they said, reuniting when Tom joined Matt in the city in 2009.
After realizing that they had run through all of the good beer destinations in the city, they decided to start home brewing. Soon they discovered a community of like-minded beer fans, with whom they shared recipes and brewing advice. After a few years, the group made the decision to found its own brewery, Vagabund Brauerei. “I read some article about how craft beer had never happened in Berlin,” Mr. Walthall said. “And I said, ‘If no one else is going to do it, then we will.’ ” Looking around, it was clear how much work they had put into the place, from the restored plasterwork ceilings to the new wooden floor. Even empty, it made for a beautiful scene, and I could easily imagine how nice Vagabund will look when filled with a crowd of the city’s new generation of beer lovers.
In a way, this came as a disappointment. Sure, Berlin has one of Europe’s most vibrant cultural scenes, but a lack of good beer had always been something I could give my friends there a hard time about. Now that was gone.
“Just like Berlin is a great town for artists and writers,” Mr. Crozier said, “it now seems like a good place for small brewers to do their thing.”
BREWPUBBING IN BERLIN
The outstanding sausages and rock-star foreign beers outrank the local craft bottles at Das Meisterstück (Hausvogteiplatz 3-4; 49-30-5587-2562; dasmeisterstueck.de).
One of the city’s first craft beer destinations, Hops & Barley Hausbrauerei, serves great small-production lagers in Friedrichshain (Wühlischstrasse 22-23; 49-30-2936-7534; hopsandbarley.eu).
A favorite of beer cognoscenti, Wedding’s Eschenbräu serves new specialty brews about twice a month (Triftstrasse 67; 49-30-462-6837; eschenbraeu.de).
Traditional fare like roast ham hocks and modern beers like rye ales bring fans to Brauhaus Südstern (Hasenheide 69; 49-30-6900-1624; brauhaus-suedstern.de). You would need to follow fire trucks in order to find a smokier pub than Bierkombinat Kreuzberg (Manteuffelstrasse 53; 49-179-142-6670; bier-kombinat.de). The brews, produced by Südstern’s Thorsten Schoppe, are excellent. BrewBaker served one of the city’s first IPAs, but its best seller is the excellent Bellevue Pils, available at various places around town. It is moving to a new location in Moabit (brewbaker.de).
A visual artist, Johannes Heidenpeter, also creates beautiful beers, selling them on weekends inside Markthalle Neun in Kreuzberg (Eisenbahnstrasse 42-43; heidenpeters.de). Vagabund Brauerei serves American-style craft beers produced by expatriate Americans (Antwerpenerstrasse 3; vagabundbrauerei.com).
The Pfefferberg building in Prenzlauer Berg is home to a theater, restaurants and, as of this summer, the new Pfefferbräu brewpub (Schönhauser Allee 175; pfefferbraeu.de).
For great bottles —  both local and imported —  and the latest news on the city’s beer scene, drop by the Berlin Bier Shop in Moabit (Kirchstrasse 23; 49-30-3910-0730; berlinbiershop.com). Specializing in German rarities, the year-old Hopfen & Malz bottle shop is just a block from Eschenbräu in Wedding (Triftstrasse 57; hopfenmalz.de).

2013年9月19日 星期四

Middle-Aged Men Can Blame Estrogen for That Waistline, Too 男性衰老,雌激素分泌不足也是關鍵

男性衰老,雌激素分泌不足也是關鍵

這是許多中年男人的痛苦:他們開始有了大肚腩,開始減少健身器械的配重,而且不知為何,沒有了年輕時候的性慾。
一個已經明確的元兇是睾酮,因為隨着時間的流逝,男人產生 的雄性激素漸漸變少。但現在還出現了一個令人驚訝的新答案。醫生稱這個答案會為有關男性身體如何變老的研究注入新的活力。結果證明,雌激素,也就是女性荷 爾蒙,在男性身體中發揮的作用遠大於之前的想像,而且,與女性一樣,雌激素水平降低會導致男性腰圍增大。
  • 檢視大圖 本·艾弗森參與了一項針對20歲至50歲男性的研究。受試者志願讓睾酮停止分泌16周。科學家們正在跟年長的男性身上重複此項研究,以衡量他們的生命力。
    Nathan Weber for The New York Times
    本·艾弗森參與了一項針對20歲至50歲男性的研究。受試者志願讓睾酮停止分泌16周。科學家們正在跟年長的男性身上重複此項研究,以衡量他們的生命力。

賓夕法尼亞大學(University of Pennsylvania)醫學教授彼得·J·斯奈德博士(Peter J. Snyder)表示,雌激素對男性的作用的相關發現是「一個重大進展」。斯奈德博士正在主持一個新的大規模研究項目——針對65歲及以上男性的激素療法。 一直以來,睾酮不足幾乎被認為是導致中年男性出現常見身體不適癥狀的唯一原因。
此項研究涉及一些新領域,比如弄清楚每一種激素對男性的作用,以及不同的激素水平如何影響身體機能。根據《新英格蘭醫學期刊》(The New England Journal of Medicine)周三發表的一篇論文,雖然睾酮水平下降是造成中年男性肌肉萎縮的原因,但雌激素水平的降低管控着脂肪的堆積。該論文提供了迄今為止最具說服力的證據,證明雌激素是導致中年男性遇到麻煩的主要因素。這兩種激素都是激發性慾所需的。
周三,哈佛大學醫學院(Harvard Medical School)內分泌學家、上述論文的第一作者喬爾·芬克爾斯坦博士(Joel Finkelstein)在新聞通稿中表示,「通常被認為是因為睾酮不足而產生的一些癥狀,實際上部分或幾乎完全是由雌激素減少引發的。」
芬克爾斯坦博士的論文只是一系列研究的開端,在很多人看來,這些研究有望讓我們對男性身體中睾酮及雌激素的作用形成一種新的認識。斯奈德博士正在主持另一項名為「睾酮臨床試驗」(Testosterone Trial)的研究。該研究測量兩種激素的水平,並探尋睾酮治療是否能使睾酮水平低的年長男性變得更年輕——使他們走得更快、感覺更有活力、增強性功能與 記憶力,並強化骨骼。小規模研究的結果讓人看到了希望,但並不可靠,而且雌激素還沒有成為考慮因素。
「我們以前忽略了男性身體中的雌激素,但我們現在正在做相 關研究,」華盛頓大學醫學院(Washington University School of Medicine)睾酮及老年病學研究員、退伍軍人事務部皮吉特灣醫療系統(V.A. Puget Sound Health Care System)研究員阿爾文·M·松本博士(Alvin M. Matsumoto)說。「在這方面,我們只是剛剛起步。」松本博士是睾酮臨床試驗項目的研究員。
無論是男性還是女性,雌激素都是由睾酮轉化而來的。男性的 睾酮水平較高,因此他們最終的雌激素水平至少是絕經女性的兩倍多。由於隨着年齡的增長,兩種激素的水平都有所降低,身體會出現一些變化。但迄今為止,研究 人員幾乎只注重研究雌激素對女性的影響,以及睾酮對男性的影響。
芬克爾斯坦博士的研究為兩種激素各自的功能及其在不同水平 下的表現給出了一份新路線圖。結果表明,不同程度的睾酮缺乏會觸發不同的癥狀。他發現,睾酮是肌肉張力和去脂體重的首要調節因素,但維持肌肉所需的睾酮水 平比之前預想的要低。年輕男性的平均水平是每100毫升血清中含有550毫微克睾酮。醫生們普遍認為,低於300毫微克的話就屬於過低,可能需要治療,而 一般的治療藥物為睾酮凝膠。
然而,芬克爾斯坦博士的研究發現,除非睾酮水平降至200毫微克以下的極低水平,肌肉力量與尺寸不會受到影響。不過,脂肪堆積會在較高的水平發生:睾酮為300到350毫微克的時候,雌激素就會降至觸發中年發福的水平。
至於性慾與性表現,兩者均需要一定的雌激素和睾酮,而且隨着這兩種激素水平的上升而穩步提高。研究人員稱,現在距離給出諸多明確建議還差很遠,不過,並不建議男性使用雌激素,因為高劑量的雌激素會導致胸部增大等女性特徵的出現。
芬克爾斯坦博士表示,儘管醫生會為每100毫升血清中睾酮 含量低於300毫微克的男性開出睾酮凝膠的處方,但這種一刀切的標準過於武斷,而且沒有臨床依據。一般情況下,男性使用激素是為了治療疲勞、抑鬱或性慾減 退等癥狀,但它們與睾酮水平低下的關係並不明確。芬克爾斯坦博士稱,數據顯示,睾酮水平在300毫微克的男性如有性問題的話,可以嘗試使用睾酮,但肌肉乏 力的人則不應歸咎於睾酮不足。不過,他還說,「睾酮水平低下的癥狀往往非常不明顯。」
目前有數百萬男性使用睾酮凝膠,促成了一個近20億美元(約合122億元人民幣)的市場。
為了進行研究,芬克爾斯坦博士及同事招募了400名20到50歲的男性。他們志願讓睾酮停止分泌16周。其中一半接受不同劑量的外來睾酮,另外一半則同時使用一種藥物,讓雌激素停止合成。這樣,研究者可以分析在沒有雌激素的情況下睾酮的效應。
芬克爾斯坦博士目前正在更年長的男性身上重複這項實驗。斯奈德博士的睾酮臨床試驗也以年長男性為研究對象。
斯奈德博士及同事招募了近800名年齡不低於65歲的睾酮 水平低下男性。其中一組人用安慰劑,另一組人則用睾酮,使得血清含量達到400到800毫微克之間。研究人員正在測試他們的行走速度、性功能、活力、記憶 力、紅細胞計數、骨骼和冠狀動脈。這項研究為期一年,將於明年完成。
研究者稱,下一步,他們希望開展一項大型研究,和2002年的一次涉及數千名女性的激素療法長期風險與益處的研究類似。比如說,他們想知道,睾酮療法是否會提高前列腺癌風險?能否預防心肌梗塞?
「我們還不清楚這些臨床問題的答案,」松本博士說。「它到底能不能預防一些很重要的東西?」
翻譯:許欣、黃錚

Middle-Aged Men Can Blame Estrogen for That Waistline, Too

It is the scourge of many a middle-aged man: he starts getting a pot belly, using lighter weights at the gym and somehow just doesn’t have the sexual desire of his younger years.
The obvious culprit is testosterone, since men gradually make less of the male sex hormone as years go by. But a surprising new answer is emerging, one that doctors say could reinvigorate the study of how men’s bodies age. Estrogen, the female sex hormone, turns out to play a much bigger role in men’s bodies than previously thought, and falling levels contribute to their expanding waistlines just as they do in women’s.


The discovery of the role of estrogen in men is “a major advance,” said Dr. Peter J. Snyder, a professor of medicine at the University of Pennsylvania, who is leading a big new research project on hormone therapy for men 65 and over. Until recently, testosterone deficiency was considered nearly the sole reason that men undergo the familiar physical complaints of midlife.
The new frontier of research involves figuring out which hormone does what in men, and how body functions are affected at different hormone levels. While dwindling testosterone levels are to blame for middle-aged men’s smaller muscles, falling levels of estrogen regulate fat accumulation, according to a study published Wednesday in The New England Journal of Medicine, which provided the most conclusive evidence to date that estrogen is a major factor in male midlife woes. And both hormones are needed for libido.
“Some of the symptoms routinely attributed to testosterone deficiency are actually partially or almost exclusively caused by the decline in estrogens,” said Dr. Joel Finkelstein, an endocrinologist at Harvard Medical School and the study’s lead author, in a news release on Wednesday.
His study is only the start of what many hope will be a new understanding of testosterone and estrogen in men. Dr. Snyder is leading another study, the Testosterone Trial, which measures levels of both hormones and asks whether testosterone treatment can make older men with low testosterone levels more youthful — by letting them walk more quickly, feel more vigorous, improve their sexual functioning and their memories, and strengthen their bones. Smaller studies have been promising but unreliable, and estrogen has not been factored in.
“We had ignored this hormone in men, but we are studying it now,” said Dr. Alvin M. Matsumoto, a testosterone and geriatrics researcher at the University of Washington School of Medicine and the V.A. Puget Sound Health Care System, who is a Testosterone Trial researcher. “We are just starting out on this road.”
Both men and women make estrogen out of testosterone, and men make so much that they end up with at least twice as much estrogen as postmenopausal women. As levels of both hormones decline with age, the body changes. But until now, researchers have focused almost exclusively on how estrogen affects women and how testosterone affects men.
Dr. Finkelstein’s study provides a new road map of the function of each hormone and its behavior at various levels. It suggests that different symptoms kick in at different levels of testosterone deficiency. Testosterone, he found, is the chief regulator of muscle tone and lean body mass, but it takes less than was thought to maintain muscle. For a young man, 550 nanograms of testosterone per deciliter of blood serum is the average level, and doctors have generally considered levels below 300 nanograms so low they might require treatment, typically with testosterone gels.
But Dr. Finkelstein’s study found that muscle strength and size turn out to be unaffected until testosterone levels drop very low, below 200 nanograms. Fat accumulation, however, kicks in at higher testosterone levels: at 300 to 350 nanograms of testosterone, estrogen levels sink low enough that middle-aged spread begins.
As for sexual desire and performance, both require estrogen and testosterone, and they increase steadily as those hormone levels rise. Researchers say it is too early to make many specific recommendations, but no one is suggesting that men take estrogen, because high doses cause feminine features like enlarged breasts.
Although doctors prescribe testosterone gels for men whose levels fall below 300 nanograms per deciliter, that cutoff point is arbitrary, and there is no clinical rationale for it, Dr. Finkelstein said. Often men take the hormone to treat complaints like fatigue, depression or loss of sexual desire, which may or may not be from low levels of testosterone. The data suggest that men with levels around 300 nanograms who complain of sexual problems may want to try testosterone, but those who complain of flagging muscle strength should not blame testosterone deficiency, Dr. Finkelstein said. But, he added, “symptoms of low testosterone tend to be quite vague.”
Today, millions of men are using testosterone gels, fueling a nearly $2 billion market.
For their study, Dr. Finkelstein and his colleagues recruited 400 men aged 20 to 50 who agreed to have their testosterone production turned off for 16 weeks. Half then received varying amounts of testosterone, while the other half also got a drug that shuts off estrogen synthesis so the researchers could assess the effects of having testosterone but not estrogen.
Now Dr. Finkelstein is repeating the study with older men. The Testosterone Trial is looking at them too.
For that study, Dr. Snyder and his colleagues recruited nearly 800 men aged 65 and older who have low testosterone levels. The men take either a placebo or enough testosterone to bring their level to between 400 and 800. Investigators are assessing walking speed, sexual functioning, vitality, memory, red-blood-cell count, bones and coronary arteries. The yearlong study will be completed next year.
Next, researchers said, they want to do a large study like one conducted with thousands of women in 2002 that asked about long-term risks and benefits of hormone therapy. Does testosterone therapy lead, for example, to more prostate cancer? Does it prevent heart attacks?
“We still don’t know the answers to the clinical questions,” Dr. Matsumoto said. “Does it prevent things that are really important?”

2013年9月13日 星期五

What Becomes of the Lost Estates?無意中按到的


這篇是我無意中按到的  紐約時報9月可免費讀10篇中的一篇
The Pour

What Becomes of the Lost Estates?

Michelle V. Agins/The New York Times
Drinking the precise, focused red Burgundies of René Engel can be a bittersweet proposition as the estate no longer exists.
  • Facebook
  • Twitter
  • Google+
  • Save
  • E-mail
  • Share
  • Print
  • Reprints
Recently I attended two extraordinary dinners in New York, one featuring the precise, focused red Burgundies of René Engel and the other the exquisite Côte-Rôties of Marius Gentaz.
Michelle V. Agins/The New York Times
To drink any one of these bottles could have been the zenith of a wonderful meal.

Readers’ Comments

Share your thoughts.
At their best, these are the sorts of wines that amplify the sense of wonder at the heart of greatness. They are reminders that no matter how rationally we try to analyze wines, they show their true measure in the emotions they evoke.
Engel and Gentaz are great examples of wines that express all the distinctive beauty of their terroirs, enhanced by the personal touch of the winemaker. These two small family estates share another important characteristic: they no longer exist.
Few passages in family businesses are more difficult to negotiate than the leadership transition from one generation to the next. At best, it occurs seamlessly, the parent ceding control to the child while remaining available to offer occasional advice and encouragement. But it may happen abruptly, after sudden illness or death. It may be fierce, as when Oedipal drama interferes with judgment.
Or, as in the case of Engel and Gentaz, an estate hits a dead end, with no heirs to carry on.
It’s in the nature of things that estates come and go. Most die off unmourned. Their wines were not distinctive enough, perhaps, to be irreplaceable. Yet for every great estate like Jean-Louis Chave of the northern Rhône, said to have made wine continuously since 1481, the annals are replete with names now consigned to history, their wines to be savored wistfully or sold at auction for outlandish prices born of increasing scarcity.
Henri Jayer, the legendary Burgundian vigneron, died in 2006 after retiring some years before. His vineyards are now farmed by his nephew by marriage, Emmanuel Rouget, whose wines are well respected but not revered.
Raymond Trollat was for years the conscience of St.-Joseph, having adhered to traditional, backbreaking agricultural methods as others were taking easier paths. He retired in 2005 with no heirs. I read recently that a bottle of his St.-Joseph had sold at auction for $600, a ridiculous price for what is essentially a rustic but soulful village wine, though perhaps not so ridiculous for the spirit of Raymond Trollat, which is irreplaceable.
Noël Verset played a similar role in Cornas, maintaining the ancient traditions of this northern Rhône village through many lean years until the rest of the world learned to appreciate the wines. Mr. Verset retired and sold off his vines, his wines surfacing occasionally like eloquent voices from the past.
Once, a friend opened a bottle of 1979 Barbaresco from Giovannini Moresco, a long-gone producer. What a beautiful legacy, pure, pale and elemental. It came and went so fast, and, sadly, I’ve never seen another bottle.
Alberico Boncompagni Ludovisi, the prince of Venosa, produced his last wonderful bottles of Fiorano, his estate within the city limits of Rome, in 1995. That year, for reasons he did not explain, he tore out his vineyard. The prince died in 2005, and after years of legal wrangling, the estate was divided among his heirs, who replanted the vineyard. One day we’ll see whether the new wines bear any relation to the old.
Continuity is easier in some regions. In Bordeaux, for example, where so many chateaus are in the hands of corporations, it’s more a matter of replacing employees and carrying on. But Bordeaux is not always so corporate. Jean-François Fillastre, the proprietor of Domaine du Jaugaret, one of my favorite small Bordeaux estates, is 70 and has no heirs. I wonder what will happen to it.
If life were fair, René Engel would still be in the hands of the Engel family. Philippe Engel took over the estate in 1981 from his father, Pierre, who died young, and by all accounts Philippe transformed a good producer into a terrific one. But he, too, died young, of a heart attack at 49 in 2005. With no heirs, it was sold to François Pinault, the billionaire who also owns Château Latour, and is now called Domaine d’Eugénie and is still discovering its personality.
At the small Engel dinner at DBGB on the Bowery, we drank six bottles of grand cru Burgundy: Clos Vougeots from 1999, ’96, ’91 and ’90, and Grands Échézeauxs from ’99 and ’98. As a group, the wines were elegant, subtle and complex, yet with a touch of rusticity that seemed to give them individuality. The ’98 Grand Échézeaux especially stood out. It was beautifully calibrated and clear, spicy, floral and bursting with energy. The ‘99 Grand Échézeaux likewise showed great finesse, while the Clos Vougeots were richer and plumper, lovely but maybe not with the same sense of intricate detail.
We toasted the memory of Philippe Engel, and those who had known him told stories of this adventurous man who enjoyed boating, parties and traveling the world.
By contrast, Marius Gentaz never went far from his home in Ampuis. In many ways, his life had more in common with the 19th century than the 21st.
He farmed less than three acres on the dizzyingly steep slopes of Côte-Rôtie, and essentially made his wines, labeled Gentaz-Dervieux, by hand. He began in wine in 1947 with his father-in-law, then worked on his own from 1952 until 1993. When he retired, his vines went to his nephew, René Rostaing, who blends them into his excellent Côte-Rôties. But they are not Gentaz-Dervieux.
At the dinner, put on at Bar Boulud by the Rare Wine Company, an importer, several dozen of us drank 14 vintages from 1993 back to 1978. To drink any one of these bottles could have been the zenith of a wonderful meal; to have 14 was overwhelming. And each seemed to have a story to tell, about a place and a man and a time when life was lived locally.
Collectively, these were gentle wines, yet with a tensile strength that belied their graceful structure. They were savory and meaty, typical of syrahs from the northern Rhône, yet complex, gorgeously fragrant, mellow yet insistent.
If I were pressed to reveal my favorites, I would say that I loved the soft ’93, the ripe ’90 and the ethereal ’83. But the ’88 was almost otherworldly in its beauty, while the ’87 was surprisingly open, full and harmonious, and the ’85 still deep and dense with a mosaic of aromas and flavors that have many years to go to express themselves fully.
It’s bittersweet to drink wines like these, knowing that each opened bottle is one less to go around. Yet it’s also a time to celebrate that part of the human spirit that allows us to see beyond ourselves, knowing that memories travel further than flesh.

2013年9月10日 星期二

樂齡 (新加坡)

演講中的樂齡可能是新加坡對老年的官方用語之一


李顯龍2013年新加坡國慶大會上的中文演講

http://www.youtube.com/watch?v=FvC6Fg0rmUo

2013年9月8日 星期日

某些電玩有益防老


Ageing is a daunting process, not least because some of the first things to fail are also the most useful, such as memory, attention and motor skills. The idea that some form of regular mental activity can postpone mental decline is not new. Now researchers have found another: playing a certain type of video game could help the elderly stay sharper for longer http://econ.st/1em4h7X